1-Introdoction The construction of earthquake-resistant engineering projects and the stability evaluation for existing buildings are a crucial issue in seismic areas. The response of constructions and their damages depend on source parameters and distance to rupture, amplitude, duration, the spectral content of vibration and local conditions of the site (soil conditions, topography, etc.; Jorjiashvili et al., 2016; Ashayeri et al., 2018). An earthquake not only destructs directly critical structures by generating the seismic waves, but also leads to geohazards such as liquefaction, settlement, sand boiling, and the turbidity of spring and well waters. In such seismically active regions, the seismic hazard analysis is inevitable. The process of assessing the design parameters of seismic ground motion is called seismic hazard analysis. Probabilistic seismic hazard analysis (PSHA) is one of the most practical approaches for quantify uncertainties about future earthquake parameters and combine them to produce an explicit description of the distribution of future shaking that may occur at a site (Backer, 2013). The method is based on the rate of a past earthquake determined from the earthquake catalog. Dezful and Shush cities are historical and second population areas in Khuzestan province. On the other hand, the presence of different faults in the region demonstrates the necessity for seismic study and risk assessment of this area. This research focuses on seismotectonic setting and seismic risk analysis of Dezful and Susa cities using the probabilistic method for 50 km radius...